Parietin as an efficient and promising anti-angiogenic and apoptotic small-molecule from Xanthoria parietina
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چکیده
منابع مشابه
Antiproliferative, Antibacterial and Antifungal Activity of the Lichen Xanthoria parietina and Its Secondary Metabolite Parietin
Lichens are valuable natural resources used for centuries throughout the world as medicine, food, fodder, perfume, spices and dyes, as well as for other miscellaneous purposes. This study investigates the antiproliferative, antibacterial and antifungal activity of the acetone extract of the lichen Xanthoria parietina (Linnaeus) Theodor Fries and its major secondary metabolite, parietin. The ext...
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چکیده ندارد.
Purification and Characterization of Two Isolectins with Arginase Activity from the Lichen Xanthoria parietina
Two glycoproteins were purified and biochemically characterized from the lichen X. parietina. Both behaved as enzymes with arginase activity and haemaglutinins. Secreted arginase (SA) contained galactose and glucose in the saccharide moiety and an isoelectric point of 4.54. The algal binding-protein (ABP) had N-acetyl-glucosamine and glucose as glycosidic residues and an isoelectric point of 3....
متن کاملThe bromoperoxidase from the lichen Xanthoria parietina is a novel vanadium enzyme.
A novel bromoperoxidase was isolated from the lichen Xanthoria parietina. The enzyme contained vanadium, which is essential for enzymic activity. Under denaturating conditions the preparation showed a single protein band with an Mr of 65,000. Thermal-denaturation studies showed that this bromoperoxidase could tolerate high temperatures. The affinity of the enzyme for its substrate bromide is hi...
متن کاملAnti-Angiogenic Activity of a Small Molecule STAT3 Inhibitor LLL12
BACKGROUND Recent data indicate the Signal Transducer and Activator of Transcription 3 (STAT3) pathway is required for VEGF production and angiogenesis in various types of cancers. STAT3 inhibitors have been shown to reduce tumor microvessel density in tumors but a direct anti-angiogenic activity has not been described. METHODOLOGY/PRINCIPAL FINDINGS We investigated the direct action of a sma...
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ژورنال
عنوان ژورنال: Revista Brasileira de Farmacognosia
سال: 2019
ISSN: 0102-695X
DOI: 10.1016/j.bjp.2019.04.012